About

I am a pharmacist and biomedical scientist, with a research focus on the application of NMR spectroscopy-based metabolomics to cell systems related to brain disorders. 

Teaching responsibilities

I am currently the module lead for Clinical Genetics (for human biology, forensic and biomedical science students) and Applied Professional Practice (for zoology, sports science and forensic science students on industrial placement). I also teach specific sessions in various forensic and biomedical science modules, including research methods, forensic anthropology, bioinformatics, etc. 

Professional interests

I love everything metabolomics - capturing the metabolic content and dynamics of any biological system. It is complex, just as life itself.

Research interests

My current research work concentrates on the interaction between brain tumour cells and cells impacting on the tumour - aiming to identify how the metabolites in the tumour microenvironment support tumour growth.

Membership of professional bodies

• General Pharmaceutical Council - Registered Pharmacist
• Biochemical Society - Early Career Membership

Qualifications

• MPharm - pharmacist 
• PhD in Life Sciences
• AFHEA

Recent conferences

Metabolomics and Human Health Gordon Research Conference and Seminar 

Recent publications

• 2020 - CDK12 inhibition reduces abnormalities in cells from patients with myotonic dystrophy and in a mouse model; Ketley A et al.; Science Translational Medicine. 2020 Apr 29;12(541): eaaz2415 
• 2018 - Dynamic metabolic patterns tracking neurodegeneration and gliosis following 26S proteasome dysfunction in mouse forebrain neurons; Geiszler PC, Ugun-Klusek A, Lawler K, Pardon MC, Yuchun D, Bai L, Daykin CA, Auer DP, Bedford L; Scientific Reports. 2018 Mar 19; 8 (1): 4883
• 2018 - NAD-biosynthetic enzyme NMNAT1 reduces early behavioral impairment in the htau mouse model of tauopathy; Rossi F, Geiszler PC, Meng W, Barron MR, Prior M, Herd-Smith A, Loreto A, Yanez Lopez M, Faas H, Pardon MC, Conforti L; Behavioural Brain Research. 2018 Feb 26; 339: 140 – 152
• 2016 - Impaired burrowing is the most prominent behavioral deficit of aging htau mice;
  Geiszler PC, Barron MR, Pardon MC; Neuroscience. 2016 Aug 4; 329: 98 – 111
• 2016 - A novel role for the immunophilin FKBP52 in motor coordination;
  Young MJ*, Geiszler PC*, Pardon MC; Behavioural Brain Research. 2016 Oct 15; 313: 97 – 110. *joint first authors
• 2013 - The journey from metabolic profiling to biomarkers: the potential of NMR spectroscopy based metabolomics in neurodegenerative disease research; Geiszler PC, Auer DP and Daykin CA; Current Metabolomics. 1(2): 160 – 179